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doi:10.2147/JPR.S127014 [DOI] [PMC free article] [PubMed] [Google Scholar] 3.OConnor AB
In the phase II trial published in the New England Journal of Medicine (2023), retatrutide demonstrated substantial weight loss efficacy, with participants achieving up to approximately 24% mean body weight reduction at the highest doses over 48 weeks
Compared with placebo, those who received 1,600 IUs (40 mcg) and 3,200 IUs (80 mcg) vitamin D experienced a 27% and 32% risk reduction, respectively
Long-term complications: fibrosis, necrosis, and sexual dysfunction While brachytherapy achieves high rates of local tumor control, the proximity of the cervix to radiosensitive pelvic organs means that even precisely delivered radiation can result in clinically significant late toxicities [11, 108]
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